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富含sn-2 DHA脂质对大脑的益处及其酶法合成综述 Review

金俊, 金青哲, 王兴国, Casimir C. Akoh

《工程（英文）》 2020年 第6卷 第4期   页码 424-431 doi: 10.1016/j.eng.2020.02.009

摘要： 甘油酯sn-2位上的DHA可以被肠黏膜更好地吸收，从而实现机体对DHA的高效利用。为了全面了解DHA对大脑的有益功能，本文系统介绍了天然油脂甘油骨架上DHA的位置分布（sn-2和sn-1,3位）特征，并讨论了DHA补充和通过肠-脑轴传递信息的潜在功能机制肠-脑轴包含的多条双向信息通道为DHA、肠道菌群和大脑健康的相互作用提供了新的研究思路。为了在日常饮食中摄入更多的sn-2 DHA，我们建议通过更为高效和经济的酯交换制造技术生产富含sn-2 DHA脂质，其中需要解决的关键技术包括强化酶的特异性和优化纯化工艺这类饮食可满足对sn-2 关键词： DHA 和 sn-2 DHA     单甘酯     大脑     肠-脑轴     结构脂质    

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酶法合成sn-2棕榈酸甘油酯的研究进展 Review

韦伟, 孙聪, 王小三, 金青哲, Xuebing Xu, Casimir C. Akoh, 王兴国

《工程（英文）》 2020年 第6卷 第4期   页码 406-414 doi: 10.1016/j.eng.2020.02.008

摘要：

人乳脂（human milk fat, HMF）是婴儿重要的能量和营养来源，甘油三酯（TAG）在人乳脂中的含量约为98%，其具有独特的分子结构HMF在甘油碳骨架sn-2位的棕榈酸（PA）含量超过70%，而在sn-1,3位高度富集多不饱和脂肪酸。研究表明，HMF中特定的TAG结构在婴儿生长过程中起重要作用。Sn-2棕榈酸甘油酯是一种结构TAG，主要由1,3-二油酸-2-棕榈酸甘油三酯组成，将其添加到婴幼儿配方奶粉中可以模拟HMF的TAG结构。结构分析的常用方法，以及一些市售sn-2棕榈酸甘油酯产品。另外，本文还对酶法合成sn-2棕榈酸甘油酯的前景进行了展望。

关键词： 结构甘油三酯     棕榈酸     人乳替代脂     酶法合成反应     sn-2棕榈酸甘油酯     定量分析    

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Development of new transient liquid phase system Au-Sn-Au for microsystem technology

Kirsten BOBZIN, Nazlim BAGCIVAN, Lidong ZHAO, Stefania FERRARA, Jan PERNE

《机械工程前沿（英文）》 2010年 第5卷 第4期   页码 370-375 doi: 10.1007/s11465-010-0107-9

摘要： In the last decade, microsystems evolved to decisive technology in many technical applications. With increasing requirements on the performance of microsystems, more and more dissimilar materials are used in the same assembly. Correspondingly, suitable joining methods are required to fulfil the requirements on good properties of joints. In this study, a new transient liquid phase (TLP) system Au-Sn-Au was developed for potential medical applications in hybrid microsystems. The high and low melting phases Au and Sn were deposited onto diverse substrates by magnetron-sputter-ion plating. The coated substrates were soldered in a microsoldering station under different conditions. The influence of soldering conditions on the microstructure and properties of the joints was investigated. Results show that the developed solder led to high-quality joints that can be used in microsystems for medical applications.

关键词： transient liquid phase     microtechnology     soldering     diffusion     physical vapor deposition (PVD)    

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hydrothermal deoxygenation of methyl palmitate to diesel-like hydrocarbons on carbon encapsulated Ni–Sn

《化学科学与工程前沿（英文）》 2023年 第17卷 第2期   页码 139-155 doi: 10.1007/s11705-022-2217-4

摘要： Porous carbon-encapsulated Ni and Ni–Sn intermetallic compound catalysts were prepared by the one-pot extended Stöber method followed by carbonization and tested for in-situ hydrothermal deoxygenation of methyl palmitate with methanol as the hydrogen donor. During the catalyst preparation, Sn doping reduces the size of carbon spheres, and the formation of Ni–Sn intermetallic compounds restrain the graphitization, contributing to larger pore volume and pore diameter. Consequently, a more facile mass transfer occurs in carbon-encapsulated Ni–Sn intermetallic compound catalysts than in carbon-encapsulated Ni catalysts. During the in-situ hydrothermal deoxygenation, the synergism between Ni and Sn favors palmitic acid hydrogenation to a highly reactive hexadecanal that easily either decarbonylate to n-pentadecane or is hydrogenated to hexadecanol. At high reaction temperature, hexadecanol undergoes dehydrogenation–decarbonylation, generating n-pentadecane. Also, the C–C bond hydrolysis and methanation are suppressed on Ni–Sn intermetallic compounds, favorable for increasing the carbon yield and reducing the H2 consumption. The n-pentadecane and n-hexadecane yields reached 88.1% and 92.8% on carbon-encapsulated Ni3Sn2 intermetallic compound at 330 °C. After washing and H2 reduction, the carbon-encapsulated Ni3Sn2 intermetallic compound remains stable during three recycling cycles. This is ascribed to the carbon confinement that effectively suppresses the sintering and loss of metal particles under harsh hydrothermal conditions.

关键词： extended Stöber method     carbon encapsulated Ni–Sn intermetallic compounds     confinement     in-situ hydrothermal deoxygenation     hydrogenation     decarbonylation    

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第三届环境、工业和能源工程国际会议(EI2E 2019)

会议日期： 2019年09月19日

会议地点： 宁夏银川

主办单位： APISE

Hexavalent chromium in drinking water: Chemistry, challenges and future outlook on Sn(II)- and photocatalyst-based

Haizhou Liu, Xuejun Yu

《环境科学与工程前沿（英文）》 2020年 第14卷 第5期 doi: 10.1007/s11783-020-1267-4

摘要： Abstract • Wide occurrence of Cr(VI) in US source drinking water. • A strong dependence of occurrence on groundwater sources. • Elucidate Redox and equilibrium chemistry of Cr(VI). • Sn(II)-based and TiO2-based reductive treatments hold extreme promise. • Key challenges include residual waste, Cr(VI) re-generation and socioeconomic drivers. Chromium (Cr) typically exists in either trivalent and hexavalent oxidation states in drinking water, i.e., Cr(III) and Cr(VI), with Cr(VI) of particular concern in recent years due to its high toxicity and new regulatory standards. This Account presented a critical analysis of the sources and occurrence of Cr(VI) in drinking water in the United States, analyzed the equilibrium chemistry of Cr(VI) species, summarized important redox reaction relevant to the fate of Cr(VI) in drinking water, and critically reviewed emerging Cr(VI) treatment technologies. There is a wide occurrence of Cr(VI) in US source drinking water, with a strong dependence on groundwater sources, mainly due to naturally weathering of chromium-containing aquifers. Challenges regarding traditional Cr(VI) treatment include chemical cost, generation of secondary waste and inadvertent re-generation of Cr(VI) after treatment. To overcome these challenges, reductive Cr(VI) treatment technologies based on the application of stannous tin or electron-releasing titanium dioxide photocatalyst hold extreme promise in the future. To moving forward in the right direction, three key questions need further exploration for the technology implementation, including effective management of residual waste, minimizing the risks of Cr(VI) re-occurrence downstream of drinking water treatment plant, and promote the socioeconomic drivers for Cr(VI) control in the future.

关键词： Chromium     Chemistry     Treatment     Future outlook    

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第四届设计、机械和材料工程国际会议(D2ME 2019)

会议日期： 2019年09月26日

会议地点： 釜山，韩国

主办单位： HKSME

第四届设计、机械和材料工程国际会议(D2ME 2019)

会议日期： 2019年09月26日

会议地点： 釜山，韩国

主办单位： HKSME

HY-2A卫星大气校正微波辐射计在轨数据定标和检验研究

王振占,张德海,赵谨,李芸

《中国工程科学》 2013年 第15卷 第7期   页码 44-52

摘要：

海洋二号（HY-2A）卫星大气校正微波辐射计（ACMR）是为雷达高度计提供大气路径延迟校正的微波辐射计。本文针对ACMR热真空定标试验的原理、方法、实施过程及试验结果进行了阐述和分析，得到了ACMR 3个频率的辐射传输系数和非线性系数，并进行了天线订正的发射前算法分析，给出了天线温度系数。利用这些系数对在轨数据进行了处理，得到了在轨天线温度转换系数，并与Jason-1、Jason-2卫星上搭载的微波辐射仪（JMR）进行了匹配比较，结果表明一致性良好。

关键词： HY-2A     ACMR     定标和检验    

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SARS-CoV-2 侵入因子——ACE2 和TMPRSS2 在围着床期胚胎和母胎界面存在表达 Article

陈伟,袁鹏,杨铭,严智强,孔思明,严杰,柳溪溪,陈依东,乔杰,闫丽盈

《工程（英文）》 2020年 第6卷 第10期   页码 1162-1169 doi: 10.1016/j.eng.2020.07.013

摘要：

在全球肆虐的严重急性呼吸系统综合征冠状病毒2（severe acute respiratory syndrome coronavirus 2,SARS-CoV-2）导致了大量人群感染，血管紧张素转化酶2（angiotensin-converting enzyme 2, ACE2）是SARS-CoV和SARS-CoV-2的受体蛋白。为了探讨SARS-CoV-2垂直传播的潜在风险，我们利用已发表的单细胞转录组数据观察了围着床期胚胎和母胎界面上ACE2和TMPRSS2（编码跨膜丝氨酸蛋白酶2）的转录表达情况结果显示，ACE2和TMPRSS2在第6天（D6）围着床期胚胎的滋养外胚层（trophectoderm, TE）细胞、妊娠第8周的合胞滋养层（syncytiotrophoblast在这三个细胞类群中，ACE2阳性表达细胞相对于阴性细胞在自噬和免疫相关过程中存在差异。

关键词： SARS-CoV-2     ACE2     垂直传播     胎盘     围着床期    

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HY-2A卫星雷达高度计设计及其在轨工作结果

许可,刘和光,姜景山

《中国工程科学》 2013年 第15卷 第7期   页码 25-32

摘要：

海洋二号（HY-2A）卫星是我国第一颗海洋动力环境卫星，雷达高度计是HY-2A卫星的主载荷之一，发射入轨后仪器工作正常，并获得了大量有效的观测数据该仪器在20 m有效波高条件下测高精度达到了4 cm，在4 m有效波高条件下测高精度达到了2 cm，其产品精度接近Jason-2卫星高度计。本文就HY-2A卫星雷达高度计系统设计和在轨初步结果进行论述。

关键词： 雷达高度计     HY-2A卫星     在轨工作    

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基于MCNP和ORIGEN2耦合程序的IHNI-1型堆裂变产物中毒及燃耗分析

张信一,赵柱民,江新标,郭和伟,陈立新,周永茂

《中国工程科学》 2012年 第14卷 第8期   页码 69-71

摘要：

为了准确地计算反应堆的裂变产物中毒和燃耗问题，开发了一套蒙特卡罗方法程序系统。利用通用的燃耗计算方法，基于MCNP和ORIGEN2，编写了相关的数据转换、截面修正、数据接口程序，实现了MCNP和ORIGEN2程序的耦合。采用堆芯精细结构划分，对医院中子照射器I型堆裂变产物中毒和燃耗进行了计算分析。

关键词： IHNI-1     MCNP     ORIGEN2     燃耗    

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多智能体系统的体系化和组织化博弈 Editorial

陆军1,王飞跃2,董琦1,魏庆来2

《信息与电子工程前沿（英文）》 2022年 第23卷 第7期   页码 991-994 doi: 10.1631/FITEE.2240000

摘要： Multi-agent system gaming (MASG) is widely applied in military intelligence, information networks, unmanned systems, intelligent transportation, and smart grids, exhibiting systematic and organizational characteristics. It requires the multi-agent system perceive and act in a complex dynamic environment and at the same time achieve a balance between individual interests and the maximization of group interests within the system. Some problems include complex system structure, uncertain game environment, incomplete decision information, and unexplainable results. As a result, the study of multi-agent game has transformed from a traditional simple game to a game facing a high-dimensional, continuous, and complex environment, which prompts an urgent need for institutionalized and systematized gaming (InSys gaming). With this background, several important tendencies have emerged in the development of InSys gaming for multi-agent systems:1. Analyzing the evolution law of MASG and establishing the InSys gaming theory model for multi-agent systemsThe organized and systematic MASG has orderly and structured characteristics, so it is necessary to establish a system game model. To study political, military, economic, and other systemic confrontation gaming problems, the first step is to analyze the system’s internal evolution characteristics and external interaction information. In addition, establishing the evolution model of InSys gaming and studying the elements, relationships, and criteria of the game evolution help provide theoretical support for the system design, decision-making planning, and other research in this field.2. Combining several artificial intelligence learning algorithms to achieve collaborative decision-making of multi-agent systemsThe current mainstream artificial intelligence learning methods all have application advantages in specific scenarios. In solving InSys gaming problems, we can combine the environmental representation ability of deep learning and the decision generation ability of reinforcement learning (RL). For example, by building a digital simulation training environment, intelligent decision algorithms and unsupervised training methods can be designed to generate a multi-agent system’s collaborative decision in a complex and unknown environment.3. Adopting a hierarchical task planning and decision-making action architecture to reduce the complexity of collaborative decision-making algorithmsWith the increase of the scale of multi-agent systems, the problems of node coupling, observation uncertainty, and interaction disorder faced by collaborative decision-making have become increasingly prominent. The complexity of solving its systematic and organized game problems has increased significantly. A multi-agent hierarchical algorithm architecture is constructed through game task decomposition, longterm planning, and real-time action decision-making. It can effectively reduce the complexity of the search process of a collaborative decision-making algorithm. In addition, it is a feasible idea for solving an organized and systematic game.4. Establishing the robustness analysis framework of the algorithm model to solve the model deviation between data-driven methods and the actual sceneWhen the training data deviates from the actual scene for data-driven methods, the algorithm’s performance will be degraded. Thus, it is necessary to study the robustness analysis framework of data-driven methods. For example, a robust algorithm model and an actual data fine-tuning method are designed to reduce the performance loss of the trained algorithm. This strategy helps support the actual deployment of data-driven methods.Game theory has become a basic analytical framework for solving problems in strategic politics, military confrontation, market economy, and so on. The object of analysis is characterized by complex systematization and organization and has been highly concerned with and valued by academic and industrial circles alike. A multi-agent system is used to model the organized and systematic game, combined with an artificial intelligence method to solve the game decision-making problem, providing a new idea for developing theories, methods, and technologies in this field.
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标题 作者 时间 类型 操作

富含sn-2 DHA脂质对大脑的益处及其酶法合成综述

金俊, 金青哲, 王兴国, Casimir C. Akoh

期刊论文

酶法合成sn-2棕榈酸甘油酯的研究进展

韦伟, 孙聪, 王小三, 金青哲, Xuebing Xu, Casimir C. Akoh, 王兴国

期刊论文

Development of new transient liquid phase system Au-Sn-Au for microsystem technology

Kirsten BOBZIN, Nazlim BAGCIVAN, Lidong ZHAO, Stefania FERRARA, Jan PERNE

期刊论文

hydrothermal deoxygenation of methyl palmitate to diesel-like hydrocarbons on carbon encapsulated Ni–Sn

期刊论文

第三届环境、工业和能源工程国际会议(EI2E 2019)

2019年09月19日

会议信息

Hexavalent chromium in drinking water: Chemistry, challenges and future outlook on Sn(II)- and photocatalyst-based

Haizhou Liu, Xuejun Yu

期刊论文

第四届设计、机械和材料工程国际会议(D2ME 2019)

2019年09月26日

会议信息

第四届设计、机械和材料工程国际会议(D2ME 2019)

2019年09月26日

会议信息

HY-2A卫星大气校正微波辐射计在轨数据定标和检验研究

王振占,张德海,赵谨,李芸

期刊论文

SARS-CoV-2 侵入因子——ACE2 和TMPRSS2 在围着床期胚胎和母胎界面存在表达

陈伟,袁鹏,杨铭,严智强,孔思明,严杰,柳溪溪,陈依东,乔杰,闫丽盈

期刊论文

王睿：硫化氢促进脂肪细胞分化、增生和肥大（2023年2月21日）

2023年03月02日

会议视频

HY-2A卫星雷达高度计设计及其在轨工作结果

许可,刘和光,姜景山

期刊论文

基于MCNP和ORIGEN2耦合程序的IHNI-1型堆裂变产物中毒及燃耗分析

张信一,赵柱民,江新标,郭和伟,陈立新,周永茂

期刊论文

王宁：CPAL一种新的心肌细胞代谢改变和焦亡调节剂（2023年2月21日）

2023年03月02日

会议视频

多智能体系统的体系化和组织化博弈

陆军1,王飞跃2,董琦1,魏庆来2

期刊论文